Which LEGO Architecture sets are the most valuable?

The LEGO 21001 - John Hancock Center (69 pieces) is the most valuable LEGO Architecture set. This set was released in 2008 with an MSRP of $19.99.

LEGO 21001 - John Hancock Center is currently valued at 191.75 which is a 859.23% gain.

Other Valuable LEGO Architecture sets

Missing out on the LEGO John Hancock Center? If you have these LEGO Architecture sets, you could still make a decent profit.

Set NameMSRPYearLatest Market ValueGain
221016 - Sungnyemun$34.992012$328.67839.32%
321027 - Berlin$29.992016$253.60745.62%
421003 - Seattle Space Needle$19.992009$111.79459.24%
521000 - Willis Tower$19.992011$103.78419.15%